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ZINGERONE.

Valuable CAS 122-48-5 / PERFUMING

Zingerone, a potent ginger-derived antioxidant, targets oxidative stress to visibly improve photo-aged skin. It helps reduce wrinkles, pigment intensity, and redness, leading to a more even and youthful complexion.

Antioxidant Anti-aging Brightening Skin protection Collagen support

Science

This ingredient acts as a strong antioxidant, scavenging free radicals and mimicking superoxide dismutase. Its derivative, Acetyl Zingerone, enhances protection against DNA damage, supports extracellular matrix integrity, and inhibits tyrosinase for brighter skin without disrupting overall pigmentation.


Research

Medium confidence
Effective range N/A
Optimal

1%

Key findings

  1. 01 Clinical dermatologic applications of ginger: a focused review

Transparency

Not commonly dusted

No specific data is available to indicate Zingerone is commonly dusted in cosmetic formulations.


The Formula

Solubility
Both
Optimal pH 4 – 7
0 7 14

Stability

Zingerone is soluble in organic solvents and aqueous buffers. Optimal stability is observed between pH 4-7, with acidic conditions (≤6.5) recommended for Acetyl Zingerone formulations.

Conflicts

  • highly alkaline components (for Acetyl Zingerone)
  • strong oxidizers (for Acetyl Zingerone)

Safety

CIR Status
Safe as used
Sensitization risk Low

The CIR Expert Panel considers ginger-derived ingredients safe as used, provided they are formulated to be non-sensitizing. The FDA also recognizes ginger as generally safe. Clinical studies with Acetyl Zingerone showed no significant itching, burning, or stinging.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Zingerone is a valuable ingredient for addressing signs of photo-aging and promoting an even skin tone due to its robust antioxidant and skin-fortifying properties.


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