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ZINC GLYCINATE.

Valuable CAS 14281-83-5 / BUFFERING

Zinc Glycinate is a chelated form of zinc combined with the amino acid glycine, designed for enhanced skin absorption. It offers multiple benefits, including reducing inflammation, regulating sebum, and combating hyper-pigmentation.

Buffering Anti-inflammatory Antioxidant Sebum regulating Collagen boosting Wound healing Hyperpigmentation reduction

Science

Glycine acts as an effective trans-dermal carrier, boosting zinc absorption and enabling its anti-inflammatory, antioxidant, and sebum-regulating effects. It also promotes collagen synthesis, aids wound healing, and inhibits tyrosinase activity to reduce hyper-pigmentation.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Ochiai et al. (reconstructed human epidermal equivalent study for melasma)
  2. 02 Gandia et al. (oral bioavailability study comparing to zinc gluconate)

Transparency

Not commonly dusted

There is no specific data indicating that Zinc Glycinate is commonly dusted in cosmetic formulations, suggesting it is typically used at effective concentrations.


The Formula

Solubility
Water
Optimal pH 6.5 – 8
0 7 14

Stability

This chelated form is stable at room temperature and over 40°C, protecting the zinc ion from degradation and maintaining product potency. A 5% aqueous solution maintains a pH between 6.5 and 8.0.

Conflicts

  • Strong oxidizing agents
  • Strong mineral acids
  • Strong organic acids
  • Heat

Safety

CIR Status
Safe with restrictions
Max tested
1%
Sensitization risk Low

The CIR Expert Panel found zinc salts, including Zinc Glycinate, safe for cosmetic use when formulated to be non-irritating. The SCCS restricts water-soluble zinc salts to a maximum of 1% elemental zinc in ready-to-use products.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Zinc Glycinate is a valuable ingredient for its enhanced skin absorption, versatility in addressing multiple skin concerns, and established safety within recommended concentrations.


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