Science
Mechanism of Action
Glycine acts as an effective trans-dermal carrier, boosting zinc absorption and enabling its anti-inflammatory, antioxidant, and sebum-regulating effects. It also promotes collagen synthesis, aids wound healing, and inhibits tyrosinase activity to reduce hyper-pigmentation.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Ochiai et al. (reconstructed human epidermal equivalent study for melasma)
- 02 Gandia et al. (oral bioavailability study comparing to zinc gluconate)
Transparency
Dusting Analysis
There is no specific data indicating that Zinc Glycinate is commonly dusted in cosmetic formulations, suggesting it is typically used at effective concentrations.
The Formula
Formulation
Stability
This chelated form is stable at room temperature and over 40°C, protecting the zinc ion from degradation and maintaining product potency. A 5% aqueous solution maintains a pH between 6.5 and 8.0.
Conflicts
- Strong oxidizing agents
- Strong mineral acids
- Strong organic acids
- Heat
Safety
Safety Profile
The CIR Expert Panel found zinc salts, including Zinc Glycinate, safe for cosmetic use when formulated to be non-irritating. The SCCS restricts water-soluble zinc salts to a maximum of 1% elemental zinc in ready-to-use products.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Zinc Glycinate is a valuable ingredient for its enhanced skin absorption, versatility in addressing multiple skin concerns, and established safety within recommended concentrations.
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References
Sources
- researchgate.net ↗
- protocolforlife.com ↗
- tcichemicals.com ↗
- ivyandfields.com ↗
- atamanchemicals.com ↗
- cityskinclinic.com ↗
- typology.com ↗
- cir-safety.org ↗
- wbcil.com ↗
- jmdrugstore.com ↗
- mubychem.com ↗
- europa.eu ↗
- cirs-group.com ↗
- hbfuyangbio.com ↗