Science
Mechanism of Action
This extract actively scavenges free radicals and inhibits key inflammatory cytokines like IL-1β, IL-6, and TNF-α. Its fermented derivative further provides antibacterial properties and reduces melanin production by inhibiting tyrosinase activity.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Comparative Study of Bioactivity and Safety Evaluation of Ethanolic Extracts of Zanthoxylum schinifolium Fruit and Pericarp
- 02 Enhanced bioactivity of Zanthoxylum schinifolium fermented extract: Anti-inflammatory, anti-bacterial, and anti-melanogenic activity
Transparency
Dusting Analysis
No data suggests this ingredient is commonly dusted.
The Formula
Formulation
Safety
Safety Profile
Safety evaluations indicate non-mutagenic activity up to 2500 µg/plate and nontoxic concentration ranges for cytotoxicity below 300 µg/mL. However, it has not been reviewed by the CIR.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While showing promising in vitro bioactivity for antioxidant, anti-inflammatory, and anti-melanogenic effects, comprehensive safety data, including CIR review and specific irritancy/comedogenicity ratings, are currently unknown.
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