Science
Mechanism of Action
This extract modulates localized sensory responses and acts as a circulatory stimulant, enhancing microcirculation. Its compounds also inhibit inflammatory pathways and demonstrate broad-spectrum antimicrobial activity.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Journal of Ethnopharmacology / A Standardized Composition Comprised of Extracts from Rosmarinus officinalis, Annona squamosa and Zanthoxylum clava-herculis for Cellulite
- 02 Learning Herbs (Alkaloid magnoflorine inhibits NF-kB and relaxes smooth muscles)
- 03 Chemical profiles of American prickly ash, botanical dietary supplements from the Zanthoxylum genera (Antimicrobial activity)
- 04 Zanthoxylum clava-herculis - Wikipedia (Chelerythrine antibacterial activity)
- 05 Learning Herbs (8-methoxypsoralen for vitiligo)
Transparency
Dusting Analysis
No specific data indicates this ingredient is commonly 'dusted' or used below effective concentrations, however, the absence of optimal percentages makes efficacy assessment challenging.
The Formula
Formulation
Stability
This extract is soluble in both water and oil, with its ethereal oil soluble in alcohol, ether, and alkaline solutions. While generally non-irritating, formulation stability or aesthetic issues may arise, with potential for increased irritation when combined with other problematic ingredients.
Safety
Safety Profile
The CIR has not reviewed this ingredient, but the FDA lists natural extractives of Zanthoxylum Americanum as GRAS. EWG rates it 'LOW' for various concerns, noting limited data availability.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This is a valuable botanical extract offering multiple benefits including microcirculation enhancement, anti-inflammatory, and antimicrobial properties, though comprehensive safety data from regulatory bodies is currently limited.
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References
Sources
- learningherbs.com ↗
- nih.gov ↗
- researchgate.net ↗
- wikipedia.org ↗
- caringsunshine.com ↗
- ncsu.edu ↗
- incidecoder.com ↗
- deascal.com ↗
- thegoodscentscompany.com ↗
- ewg.org ↗
- paulaschoice.fr ↗
- herbalapothecaryuk.com ↗
- henriettes-herb.com ↗