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ZANTHOXYLUM AMERICANUM/CLAVA-HERCULES BARK EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Zanthoxylum Americanum/Clava-Hercules Bark Extract is a botanical ingredient recognized for its skin conditioning, anti-inflammatory, and antimicrobial properties. It also promotes microcirculation, potentially improving skin elasticity and reducing the appearance of cellulite.

skin conditioning fragrance anti-inflammatory antimicrobial circulatory stimulant

Science

This extract modulates localized sensory responses and acts as a circulatory stimulant, enhancing microcirculation. Its compounds also inhibit inflammatory pathways and demonstrate broad-spectrum antimicrobial activity.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Journal of Ethnopharmacology / A Standardized Composition Comprised of Extracts from Rosmarinus officinalis, Annona squamosa and Zanthoxylum clava-herculis for Cellulite
  2. 02 Learning Herbs (Alkaloid magnoflorine inhibits NF-kB and relaxes smooth muscles)
  3. 03 Chemical profiles of American prickly ash, botanical dietary supplements from the Zanthoxylum genera (Antimicrobial activity)
  4. 04 Zanthoxylum clava-herculis - Wikipedia (Chelerythrine antibacterial activity)
  5. 05 Learning Herbs (8-methoxypsoralen for vitiligo)

Transparency

Not commonly dusted

No specific data indicates this ingredient is commonly 'dusted' or used below effective concentrations, however, the absence of optimal percentages makes efficacy assessment challenging.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

This extract is soluble in both water and oil, with its ethereal oil soluble in alcohol, ether, and alkaline solutions. While generally non-irritating, formulation stability or aesthetic issues may arise, with potential for increased irritation when combined with other problematic ingredients.


Safety

CIR Status
Not reviewed
Sensitization risk Low

The CIR has not reviewed this ingredient, but the FDA lists natural extractives of Zanthoxylum Americanum as GRAS. EWG rates it 'LOW' for various concerns, noting limited data availability.


Your Skin

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This is a valuable botanical extract offering multiple benefits including microcirculation enhancement, anti-inflammatory, and antimicrobial properties, though comprehensive safety data from regulatory bodies is currently limited.


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