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Ingredient directory

Xylitan Sesquicaprylate

Xylitan Sesquicaprylate is a multifunctional ingredient acting as an antimicrobial, humectant, and emulsifier. It supports skin barrier function while boosting preservative efficacy in formulations.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

Antimicrobial Deodorant Humectant Skin Conditioning Surfactant Emulsifying Preservative Booster

Science

Mechanism of Action

This amphipathic compound enhances skin hydration by attracting water and supporting the lipid barrier. It inhibits microbial growth and stabilizes oil-in-water formulations by reducing surface tension at interfaces.

Research

Clinical Evidence

Medium confidence
Effective range 0.35–0.45%
Optimal

N/A

Key findings

  1. 01 In vitro studies showed 0.35% exhibited deodorant activity against Staphylococcus epidermidis, Staphylococcus aureus, and Corynebacterium xerosis.
  2. 02 A 0.45% concentration in a mouthwash reduced several gram-positive and gram-negative bacteria, though not S. mutans.

Transparency

Dusting Analysis

Not commonly dusted

No specific data available on dusting behavior for Xylitan Sesquicaprylate.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Its amphipathic nature promotes stable emulsion formation by acting at both aqueous and water-oil interfaces.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While related Xylitol is CIR-reviewed as safe, Xylityl Sesquicaprylate itself lacks individual assessment. No SCCS or FDA cosmetic status was found.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Xylitan Sesquicaprylate is a versatile ingredient offering antimicrobial, hydrating, and emulsifying benefits, making it a valuable addition for stable, skin-compatible formulations.

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Barrier support ↗

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