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XYLENE.

Avoid CAS 1330-20-7 / 95-47-6 / 108-38-3 / FRAGRANCE, PERFUMING, SOLVENT

Xylene is a hazardous organic solvent primarily used in industrial applications, known for its ability to dissolve natural skin oils. Its defatting action can lead to significant skin irritation, dryness, and increased permeability to other substances.

Solvent Degreasing

Science

As an organic solvent, xylene strips the skin's natural protective oils, causing defatting, irritation, and dryness, while also making the skin more permeable. Its exact mechanism of systemic toxicity may involve interaction with neuronal membranes.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Xylene is a hazardous industrial solvent, not an ingredient suitable or intended for cosmetic formulations, thus dusting is not a relevant concern.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Stable under recommended industrial storage conditions.

Conflicts

  • strong oxidizers
  • strong acids
  • some forms of plastics
  • rubber
  • coatings

Safety

CIR Status
Not reviewed
Sensitization risk High

Xylene is an industrial solvent that can severely irritate, defat, crack, and peel skin upon contact. While percutaneous absorption is slow, it can contribute to systemic toxicity, and it is not reviewed or intended for direct cosmetic use.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity High

Our Assessment

Avoid

Due to its high irritancy, comedogenicity, and hazardous nature as a defatting industrial solvent, xylene should be strictly avoided in all skincare applications.


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