Science
Mechanism of Action
It functions as a potent antioxidant, safeguarding skin from oxidative stress, and exhibits significant anti-inflammatory actions by inhibiting pro-inflammatory mediators. Xanthohumol also improves skin elasticity by supporting collagen and elastin, provides antibacterial effects against acne-causing bacteria, and offers skin brightening by inhibiting tyrosinase.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 US Patent Application US20110207697A1
Transparency
Dusting Analysis
No specific data indicates that Xanthohumol is commonly dusted in cosmetic formulations, suggesting it is not a primary concern for this ingredient.
The Formula
Formulation
Stability
Xanthohumol is highly hydrophobic and largely insoluble in water, but readily soluble in organic solvents like ethanol and DMSO. It is susceptible to degradation and isomerization when exposed to high temperatures, light, and higher pH values.
Conflicts
- High pH
- High temperatures
- Light exposure
Safety
Safety Profile
Xanthohumol itself has not been reviewed by CIR, though the CIR Expert Panel has assessed Humulus Lupulus (Hops) Extract and Oil. In vitro studies show very low to no toxicity in human skin fibroblasts and other cell types, and an oral clinical trial found high-purity Xanthohumol safe and well-tolerated.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This potent hop-derived compound offers a broad spectrum of benefits, from combating aging and inflammation to addressing acne and hyperpigmentation, making it a promising multi-functional ingredient for diverse skin concerns.
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