Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

WITHANIA SOMNIFERA CALLUS EXTRACT.

Insufficient Data / SKIN CONDITIONING, SKIN PROTECTING

This potent antioxidant shields skin from digital pollution and blue light, while actively repairing existing damage. It aids skin in stress recovery, promoting hydration, elasticity, and strength for a youthful and radiant complexion.

Summary

Antioxidant Hair conditioning Humectant Moisturizing Skin conditioning Skin protecting Smoothing Soothing

Science

Mechanism of Action

It combats free radicals, inhibits collagen-degrading enzymes (MMP-1), and prevents type 1 collagen collapse by modulating cellular pathways. The extract also reduces AGEs and maintains ECM-integrin interaction, delaying skin aging.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Specific clinical studies with effective concentrations for topical application of Withania Somnifera Callus Extract on human skin are not readily available.

Transparency

Dusting Analysis

Not commonly dusted

Information regarding the common practice of 'dusting' this specific extract in formulations is not available in the provided research data.

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Stable within a neutral pH range of 4-7; callus culture media often set to pH 5.7-5.8. Controlled temperature and humidity are crucial to prevent the degradation of active compounds like withaferin A and withanolide A.

Conflicts

  • Cytotoxic withanolide aglycones

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific CIR or SCCS safety assessments exist for this callus extract. While related root extracts are often considered safe, EWG classifies 'Withania Somnifera Root Extract' as 'Restricted' without adequate substantiation. Safety data is primarily for root extracts, not specifically callus.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Insufficient Data

While exhibiting promising antioxidant and protective mechanisms, specific human topical clinical efficacy and safety data for Withania Somnifera Callus Extract remain limited, necessitating further research for precise applications.

Related

Similar Ingredients

Finding similar ingredients…