Science
Mechanism of Action
This ferment modulates immune responses, stimulates natural defense mechanisms, and significantly strengthens the skin barrier. It works by binding to TLR2, increasing skin resistance, and improving stratum corneum renewal.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 0.002% significantly increased skin barrier components like filaggrin and claudin-1 when combined with Vichy Volcanic Mineralizing Water (VVMW).
- 02 0.1% modulated immune responses, increasing antimicrobial peptides and reducing pro-inflammatory markers in stimulated cells with VVMW.
- 03 In vivo, it increased stratum corneum renewal rate to 17.3 days compared to 20.7 days in untreated skin.
- 04 It demonstrated protective activity against irritation by reducing increased blood flow post-methyl nicotinate application.
- 05 0.2% enhanced the growth of beneficial Staphylococcus epidermidis in vitro.
Transparency
Dusting Analysis
No data suggests Vitreoscilla Ferment is commonly dusted, indicating it likely retains efficacy at typical cosmetic concentrations.
The Formula
Formulation
Stability
The bacterium is cultured at pH 7.2, with some activity observed at pH 6. An optimal pH of 7.0 is noted for Vitreoscilla hemoglobin's peroxidase activity, but a general optimal range for cosmetic formulation stability is not explicitly stated.
Synergies
- Vichy Volcanic Mineralizing Water (VVMW)
Safety
Safety Profile
Vitreoscilla Ferment is generally considered safe for topical use. While not CIR reviewed, EWG Skin Deep rates it 'LOW' for common safety concerns including allergies and immunotoxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Vitreoscilla Ferment is a valuable probiotic-derived ingredient that comprehensively supports skin health by strengthening the barrier, balancing the microbiome, and reducing inflammation.
Related
Similar Ingredients
Finding similar ingredients…