Science
Mechanism of Action
This extract leverages polyphenols, including resveratrol, as potent antioxidants to reduce oxidative stress. It supports skin firmness by inhibiting elastase, brightens tone by inhibiting tyrosinase, and soothes irritation through anti-inflammatory actions, while also boosting hydration.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Inhibited anti-tyrosinase activity by ~54% (in vitro at 1 mg/mL).
- 02 Inhibited anti-elastase activity by ~98% (in vitro at 1 mg/mL).
- 03 Exhibited anti-inflammatory capacity by inhibiting Nitric Oxide production up to 35.25% (in vitro at 5.00-75.00 µg/mL).
- 04 Showed high efficacy against Gram-positive bacteria (in vitro at 200 mg/mL).
Transparency
Dusting Analysis
No data available to suggest this ingredient is commonly dusted.
The Formula
Formulation
Stability
Polyphenols within grape stem extracts are susceptible to degradation by heat, light, pH variations, enzymes, metal ions, and oxygen. Stability in aqueous solutions is optimal between pH 2 and 8.
Safety
Safety Profile
The CIR Expert Panel deemed Vitis Vinifera (Grape) Stem Extract and 23 other grape-derived ingredients safe in cosmetic use, with most irritation and sensitization tests yielding negative results.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Vitis Vinifera Stem Extract is a valuable multi-functional ingredient, offering significant antioxidant, anti-aging, brightening, and anti-inflammatory benefits with good skin compatibility and safety.
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References
Sources