Science
Mechanism of Action
Its polyphenols, including proanthocyanidins and resveratrol, act as potent antioxidants, neutralizing free radicals and reducing oxidative stress. It also inhibits pro-inflammatory molecules like IL-8 and suppresses melanin for an even skin tone.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Vitis vinifera leaf extract showed protective effects against UV and stimulated anti-aging genes (SIRT1, HSP47) in human dermal fibroblasts.
- 02 Aqueous leaf extract inhibited IL-8 secretion in human keratinocytes, demonstrating anti-inflammatory action.
- 03 Grape seed extract significantly suppressed melanin formation in UV-induced hyperpigmentation.
- 04 Vitis vinifera var. Benitaka skin extract showed an in vitro SPF of 18.56 and UVA protection.
Transparency
Dusting Analysis
Vitis Vinifera is a well-regarded ingredient with diverse, scientifically supported benefits, making it a valuable addition rather than a token inclusion.
The Formula
Formulation
Stability
Extracts are generally water-soluble, while seed oil is oil-soluble. Polyphenols are hydrophilic, often requiring technology like phytosomes for enhanced skin penetration.
Safety
Safety Profile
The CIR Expert Panel concluded Vitis Vinifera-derived ingredients are safe as used up to 10%. Certain grape varieties may cause allergic reactions, and patch testing is recommended for highly sensitive individuals.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Vitis Vinifera is a highly versatile and well-tolerated ingredient, offering comprehensive antioxidant, anti-inflammatory, and anti-aging benefits suitable for all skin types.
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References
Sources