Science
Mechanism of Action
This extract combats free radicals, inhibits elastase and tyrosinase activity to improve elasticity and reduce hyperpigmentation, and soothes irritation by reducing nitric oxide production.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Grape stem extracts exhibited anti-aging effects by inhibiting anti-tyrosinase activity by approximately 54% and anti-elastase activity by approximately 98%.
- 02 Grape stem extracts demonstrated anti-inflammatory capacity by inhibiting Nitric Oxide production up to 35.25%.
- 03 Grape stem extracts showed high antioxidant activity, with red grape stem extracts exhibiting EC50 values of 0.14-0.37 g dm/g DPPH.
Transparency
Dusting Analysis
No information in the provided research data suggests this ingredient is commonly dusted or typically used at ineffective concentrations.
The Formula
Formulation
Stability
Optimal extraction conditions for phenolic antioxidants from grape stems often use ethanol:water mixtures and elevated temperatures, suggesting good stability for extraction purposes. Aqueous extraction is also effective.
Safety
Safety Profile
The CIR Expert Panel considers Vitis vinifera (grape)-derived ingredients, including stem extracts, safe for cosmetic use. General grape extracts are noted as mild, emphasizing the need to limit pesticide residues and heavy metals.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A potent antioxidant, anti-aging, and anti-inflammatory ingredient, suitable for various skin types and generally well-tolerated.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources