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Moumoujus

VITEX NEGUNDO LEAF CELL EXTRACT.

Valuable CAS 92347-33-6 / FRAGRANCE, SKIN PROTECTING

Vitex Negundo Leaf Cell Extract is a multi-functional ingredient known for its skin conditioning, antioxidant, and anti-inflammatory benefits. It helps maintain skin health by providing hydration, improving texture, and combating oxidative stress.

Summary

skin conditioning antioxidant antimicrobial humectant anti-inflammatory

Science

Mechanism of Action

This extract works by conditioning the skin, offering humectant and antimicrobial properties, and acting as a potent antioxidant. It significantly reduces inflammation by downregulating NF-κB signaling and inhibiting pro-inflammatory cytokines.

Research

Clinical Evidence

Medium confidence
Effective range 0.00156–0.06%
Optimal

0.05%

Key findings

  1. 01 Phytochemical Profiling and Antioxidant activity of aqueous leaf extract of Vitex negundo
  2. 02 In-vitro-Scientific evaluation of anti-inflammatory potential of leaf extracts from Vitex negundo: as a promising future drug candidate
  3. 03 Aqueous leaf extract of Vitex negundo modulates M1-M2 phenotypic switch and functional changes in human macrophages in an in vitro model of hypertension
  4. 04 In vitro Antioxidant Activity of Vitex negundo L. Leaf Extracts

Transparency

Dusting Analysis

Not commonly dusted

No specific data on dusting behavior or thresholds were found for this ingredient.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While generally well-tolerated, patch testing is recommended as skin irritation or allergic reactions are uncommon potential side effects. In vitro studies show non-toxic levels up to 0.05% for human cells.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

This versatile extract offers significant antioxidant, anti-inflammatory, and conditioning benefits, making it a valuable addition for various skin concerns.

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