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Moumoujus

VIOLACEIN.

Insufficient Data CAS 548-54-9 / ANTIMICROBIAL, ANTIOXIDANT, COLORANT

Violacein is a naturally occurring pigment with a broad spectrum of biological activities, including antibacterial, anti-inflammatory, and antioxidant properties. It holds potential for targeted applications in acne treatment and skin protection.

Summary

Antibacterial Anti-inflammatory Antioxidant Antifungal Immunostimulatory Anti-acne

Science

Mechanism of Action

This active works by inhibiting bacterial growth, particularly against acne-related bacteria like P. acnes and S. aureus. It also activates the human Toll-like Receptor 8 (TLR8) pathway, providing immunostimulatory and anti-inflammatory benefits, alongside antioxidant effects.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Two studies mentioned in 'Violacein: Properties and Production of a Versatile Bacterial Pigment'.
  2. 02 'Recent Advances in Synthetic, Industrial and Biological Applications of Violacein and Its Heterologous Production'.
  3. 03 'Violacein: a natural antibacterial agent empowered by film-forming sprays for topical applications'.

Transparency

Dusting Analysis

Not commonly dusted

No information regarding dusting characteristics was found in the available research data.

The Formula

Formulation

Solubility
Oil
Optimal pH 2 – 12
0 7 14

Stability

Violacein demonstrates stability across a wide pH range of 2-12, although optimal stability is noted between pH 5-9. It is susceptible to degradation from prolonged light exposure and oxidation.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

While listed in the FDA Global Substance Registration System (GSRS), specific 'safe as used' or 'restricted' statuses for cosmetic applications are not available. No safety assessments by CIR or SCCS were found.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Violacein shows promising antibacterial and antioxidant properties for skin health, but further safety and efficacy studies in cosmetic applications are needed before a definitive recommendation.

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