Science
Mechanism of Action
It works by inhibiting pro-inflammatory mediators and upregulating key proteins like CD44 and aquaporin-3 in keratinocytes, thereby improving skin barrier function and hydration.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Oral Viola yedoensis Makino formula (150-600 mg/kg daily) alleviated DNCB-induced atopic dermatitis in mice, reducing inflammation and T cell responses.
- 02 Viola yedoensis ethanol extract (150 µg/mL in vitro) inhibited nitric oxide production by over 90% in LPS-stimulated macrophages.
- 03 Upregulated CD44 by 15% and aquaporin-3 (AQP3) by 78% in human keratinocytes, demonstrating improved skin barrier function and hydration.
Transparency
Dusting Analysis
There is no specific data available regarding Viola Yedoensis Extract being commonly dusted or typical dusting thresholds.
The Formula
Formulation
Stability
Ethanolic extracts show good stability in hydroalcoholic solutions. Enhanced stability of its abundant flavonoids and coumarins is attributed to glycosylation.
Safety
Safety Profile
Generally considered safe with a low hazard rating for cancer, allergies, and reproductive toxicity by EWG. A skin tolerance test is recommended for botanical ingredients.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Viola Yedoensis Extract offers significant anti-inflammatory, hydrating, and barrier-supporting benefits, making it a valuable ingredient for sensitive and problematic skin types.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources
Keep exploring
From ingredients to everyday care.
Sensitive skin ↗
Start with comfort, product choices and the questions to ask.
Barrier support ↗
Understand moisture, lipids and the limits of ingredient claims.
Ingredient names help you read a label. They do not establish how a finished product will perform. Explore The Garden.