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VERNONIA APPENDICULATA LEAF EXTRACT.

Valuable CAS 892873-85-7 / SKIN PROTECTING

Vernonia Appendiculata Leaf Extract strengthens the dermal-epidermal junction and activates fibroblast synthesis, improving overall skin status. It also offers comprehensive protection against environmental stressors and supports skin cohesion.

Antioxidant Skin-Protecting Skin Firming Anti-aging

Science

It upregulates key proteins like Cytokeratin 14 and Laminin V for DEJ integrity, while activating fibroblasts to synthesize dermis compounds. Furthermore, it protects the collagen network via anti-glycation and MMP-1 inhibition, providing antioxidant defense.


Research

Medium confidence
Effective range 1–7%
Optimal

1%

Key findings

  1. 01 Upregulates Cytokeratin 14 and Laminin V content, significantly strengthening the dermal-epidermal junction (ex vivo on skin biopsies).

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The extract is often prepared in a water-glycerin blend for optimal stability.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Side effects are generally uncommon, but a patch test is recommended. Data regarding topical use during pregnancy and breastfeeding is currently lacking.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This ingredient is valuable for enhancing skin structure and resilience, offering significant anti-aging and protective benefits through its unique mechanism.


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