Science
Mechanism of Action
This extract inhibits tyrosinase, a key enzyme in melanin synthesis, thereby reducing hyperpigmentation. It also scavenges free radicals and enhances intracellular antioxidant enzymes, providing anti-inflammatory properties.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Subcritical water extract (SWE) and hot water extract demonstrated significant tyrosinase inhibitory activity, with IC50 values as low as 11.81 ± 0.52 μg/mL for SWE. A key polyphenol, 6′-O-caffeoylarbutin, showed stronger melanin inhibition (IC20 of 63.89 µM) than arbutin in a zebrafish model, effective at 60 µM (lowest non-toxic level).
Transparency
Dusting Analysis
The Formula
Formulation
Conflicts
- Magnesium stearate (demonstrated chemical interaction with a related Vaccinium species)
Safety
Safety Profile
The ingredient is not CIR reviewed and may pose a likelihood of irritation, inflammation, or dryness, particularly when combined with other problematic components.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A potent antioxidant and skin brightener, offering precise melanin inhibition, though caution regarding potential irritation is warranted.
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References
Sources
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