Science
Mechanism of Action
Usnic acid and polyphenols target Gram-positive bacteria and fungi, reducing proliferation and inflammation. It neutralizes reactive oxygen species, protecting against oxidative stress, and may support wound healing.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The initial oil extract had a pH of 4; a bioadhesive oral film using it in canola oil was pH 6.97. Usnic acid, a key component, is more soluble in organic solvents than water.
Safety
Safety Profile
FDA warnings for oral usnic acid liver toxicity do not apply topically. While generally well-tolerated with low irritancy, it may cause allergic reactions. Patch testing is advised due to potential cytotoxicity at higher topical concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A valuable multi-functional ingredient providing antimicrobial, antioxidant, and anti-inflammatory benefits, though patch testing is recommended due to potential sensitivity at higher concentrations.
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References
Sources