Science
Mechanism of Action
It acts as a potent antioxidant by reducing reactive oxygen species and safeguarding the extracellular matrix, while its anti-inflammatory effects involve inhibiting COX enzymes and pro-inflammatory cytokines. Furthermore, it helps regulate sebum production by inhibiting 5α-reductase and offers antibacterial action.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 A 2023 in vitro study found an extract containing 64.9 µg/mL chlorogenic acid and 114.4 µg/mL caffeoylmalic acid effectively reduced ROS and protected human skin fibroblasts from H2O2-induced cytotoxicity.
- 02 Another 2023 in vitro study demonstrated antibacterial activity with a lowest MIC of 0.19 mg/mL against E. coli, and polyphenol-rich fractions significantly reduced ROS and pro-inflammatory cytokines in stimulated fibroblasts.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Soluble in both water and alcohol, suggesting versatility in formulation, though further stability testing is recommended for specific products.
Safety
Safety Profile
Generally considered safe and well-tolerated with low irritancy. While explicit formal CIR review status was not directly found, industry sources indicate general safety. Patch testing is advised for sensitive individuals.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A valuable botanical extract offering comprehensive benefits, including potent antioxidant and anti-inflammatory protection, alongside sebum regulation and antibacterial action.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources