Science
Mechanism of Action
This extract combats oxidative stress by reducing reactive oxygen species (ROS) and protects skin structure through inhibiting elastase and collagenase enzymes. It further supports skin health by increasing cellular proliferation and migration, thereby aiding natural wound healing processes.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 In vitro, it protected human skin fibroblasts against H2O2-induced oxidative stress and cytotoxicity, effectively reducing ROS levels. Key active compounds identified were chlorogenic acid (64.9 µg/mL) and caffeoylmalic acid (114.4 µg/mL).
- 02 Studies revealed increased proliferation rates in HEK-293 (up to 39% in 24h) and HaCaT cells (up to 30% in 24h), alongside a two-fold increase in cell migration and reduced inflammation, contributing to faster wound healing.
- 03 It demonstrated anti-aging potential by inhibiting elastase and collagenase enzyme activities, with these effects attributed to ursolic acid and quercetin present in the extract.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Store in a cool, dry place at room temperature (23-25°C). Avoid extreme temperatures and do not freeze to maintain stability.
Conflicts
- strong oxidizers
Safety
Safety Profile
Urtica Dioica Extract is considered safe and generally well-tolerated for cosmetic use, being non-comedogenic and typically non-irritating. Patch testing is recommended for individuals with sensitive skin or known allergies.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Urtica Dioica Extract is a valuable, multifaceted botanical for skincare, delivering broad-spectrum benefits from anti-aging to soothing, suitable for all skin types with low irritation risk.
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