Science
Mechanism of Action
This extract acts as a powerful antioxidant by neutralizing free radicals with its rich content of polyphenols and flavonoids. It reduces inflammation by inhibiting 5-lipoxygenase activity and downregulating pro-inflammatory cytokines, while also inhibiting collagenase and elastase to maintain skin firmness.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Urtica dioica extract demonstrated significant antioxidant properties, effectively reducing reactive oxygen species (ROS) in H2O2-stimulated human skin fibroblasts, maintaining cell viability.
- 02 Nettle extracts showed inhibitory effects on collagenase and elastase enzymes, contributing to anti-aging potential by supporting skin firmness.
- 03 As part of a mixed extract, nettle exhibited antibacterial properties against Cutibacterium acnes (MIC < 1/2048 µg/mL), indicating potential in anti-blemish treatments.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel and SCCS have not directly assessed Urtica dioica extract. While generally well-tolerated, patch testing is advisable for individuals with sensitive skin or known allergies.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Urtica Dioica is a valuable, versatile botanical ingredient offering broad-spectrum benefits including antioxidant protection, anti-aging support, and sebum regulation, making it suitable for diverse skin concerns with a low risk of irritation.
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References
Sources