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URSOLIC ACID.

Valuable CAS 77-52-1 / FRAGRANCE, PERFUMING, SKIN CONDITIONING

Ursolic Acid is a potent triterpenoid compound revered for its comprehensive skin benefits, including antioxidant protection, anti-inflammatory action, and support for skin structure. It targets premature aging and improves overall skin health, suitable for various skin concerns.

Antioxidant Anti-inflammatory Skin-conditioning Soothing Antimicrobial Collagen Booster Elasticity Enhancer Skin Repair Barrier Strengthener Melanin Inhibitor Sebum Regulator

Science

It functions as a powerful antioxidant, mitigating oxidative stress and premature aging. Ursolic acid reduces inflammation, boosts collagen synthesis while inhibiting its degradation, and interferes with melanin production, leading to firmer, more even-toned skin.


Research

High confidence
Effective range 0.1–0.5%
Optimal

0.1%

Key findings

  1. 01 At 0.1%, it inhibited MMP-1 expression by 35% and induced type I collagen synthesis by 28%.
  2. 02 At 0.5%, it showed anti-inflammatory effects and induced apoptosis in keratinocytes within in vitro psoriasis models.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Ursolic acid is lipophilic with poor solubility in both water and most organic solvents, making formulation challenging. It is susceptible to oxidation and discoloration at high temperatures, requiring advanced delivery systems for bioavailability.

Conflicts

  • Introduce gradually with other active ingredients like retinoids or exfoliating acids to avoid overstimulation of the skin.

Safety

CIR Status
Not reviewed
Max tested
0.5%
Sensitization risk Low

Generally recognized as safe for cosmetic use within its maximum recommended concentrations of 0.5% for personal care and 0.06% for eye care. Patch testing is recommended for sensitive skin, as high doses may lead to irritation.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Ursolic Acid is a valuable multi-functional ingredient offering significant anti-aging, anti-inflammatory, and reparative benefits for a wide range of skin types.


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