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URIDINE.

Insufficient Data CAS 58-96-8 / SKIN CONDITIONING, SKIN PROTECTING

Uridine is a crucial biomolecule involved in fundamental cellular functions and energy metabolism, frequently incorporated into anti-aging and skin conditioning formulations.

Anti-inflammatory Cell Growth DNA Repair Hydration Collagen Support Skin Conditioning Skin Protecting

Science

It supports immune signaling pathways, potentially reducing inflammatory responses by modulating cytokines like TNF-α and IL-1β. Furthermore, uridine enhances DNA repair, cell growth, and the biosynthesis of key skin components such as hyaluronic acid and collagen.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Stock solutions of uridine in water at pH 7 are stable for several days when stored at 4 °C. It is also soluble in organic solvents like DMSO, dimethyl formamide, and methanol.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Uridine has not been reviewed by the CIR or SCCS for cosmetic use. While its derivative, uridine triacetate, is FDA-approved orally, this does not confer specific cosmetic ingredient status for uridine.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

Uridine shows promising mechanistic benefits for skin health; however, there is insufficient specific topical cosmetic efficacy and safety data from regulatory bodies to confidently assess its full potential.


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