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URIC ACID.

Valuable CAS 69-93-2 / BUFFERING, SKIN CONDITIONING

Uric Acid is a versatile ingredient that functions as a skin conditioning agent and pH regulator, aiding in product stability. It also acts as an antioxidant, supporting overall skin health.

Antioxidant Skin-conditioning pH adjuster / buffer

Science

As a potent antioxidant, it neutralizes oxygen free radicals and promotes tissue repair by initiating necessary inflammatory processes. Additionally, it helps mobilize progenitor endothelial cells and maintains formulation pH.


Research

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In a combination with uricase, total active substances at 0.5-3% demonstrated various actions including keratinization, protein hydrolysis, and water-binding. This data is for the combined effect.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5.4 – 6
0 7 14

Stability

Uric acid is sparingly soluble in water but solubility increases with pH, particularly around its pKa1 of 5.4. It is stable but should avoid strong acids, bases, and oxidizing agents.

Synergies

  • Uricase

Conflicts

  • strong acids
  • strong bases
  • oxidizing agents

Safety

CIR Status
Not reviewed
Sensitization risk Low

Not specifically reviewed by CIR or SCCS. However, EWG rates it 'LOW' for various concerns including immunotoxicity, and it is not classified as an endocrine disruptor at concentrations ≥ 0.1%.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Uric Acid is a valuable ingredient for its antioxidant, skin-conditioning, and pH-regulating properties, suitable for all skin types due to low safety concerns.


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