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UNDECANE.

Valuable CAS 1120-21-4 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Undecane is a lightweight, non-greasy emollient that forms a protective film on the skin's surface, enhancing moisture retention and promoting a smoother, more supple feel. Beyond its conditioning properties, it offers anti-inflammatory and anti-allergic benefits by modulating cellular pathways, making it suitable for a wide range of skin types, including sensitive skin, with a low comedogenic risk.

emollient skin conditioning solvent anti-inflammatory anti-allergic

Science

As an emollient and skin conditioning agent, undecane functions by establishing a subtle, protective barrier that mitigates transepidermal water loss (TEWL), thereby optimizing skin hydration and refining texture. It imparts a distinctive dry, silky feel with rapid absorption, frequently serving as a bio-derived alternative to silicones. Moreover, undecane exhibits anti-inflammatory and anti-allergic capabilities, specifically by elevating intracellular cAMP levels within mast cells and keratinocytes. This action inhibits mast cell degranulation, diminishes the release of inflammatory mediators such as histamine and TNF-α, and reverses increased p38 phosphorylation and NF-κB transcriptional activity in sensitized skin cells.


Research

Medium confidence
Effective range 2–10%
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Undecane demonstrates chemical stability under standard ambient and recommended storage conditions. It remains stable at room temperature and does not typically react with most chemicals. Heating to decomposition should be avoided as it may release acrid smoke and irritating fumes.

Conflicts

  • strong oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
10%
Pregnancy
Caution
Sensitization risk Low

Undecane is generally regarded as safe for use in cosmetic formulations, exhibiting a low potential for adverse reactions. It possesses a low comedogenic rating of 1, indicating a minimal likelihood of pore obstruction. While side effects are rare, mild skin irritation, such as redness or itching, may manifest in individuals with sensitive skin or existing allergies. Data concerning topical use during pregnancy and breastfeeding is limited, and consultation with a healthcare professional is advised for these populations. Safety data sheets confirm it is not classified as acutely toxic, corrosive, irritant to skin or eyes, a respiratory or skin sensitizer, germ cell mutagenic, or carcinogenic.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Undecane is a valuable ingredient prized for its lightweight emollience, rapid absorption, and anti-inflammatory properties, making it well-suited for improving skin hydration and calming sensitive complexions across various cosmetic applications.


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