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Moumoujus

UNCARIA TOMENTOSA BARK POWDER.

Valuable / SKIN CONDITIONING

Uncaria Tomentosa Bark Powder, often known as cat's claw, is a botanical extract rich in active compounds. It provides robust antioxidant and anti-inflammatory properties, effectively protecting the skin from oxidative stress and reducing inflammation while supporting overall skin regeneration.

Summary

Skin-conditioning Antioxidant Anti-inflammatory Antimicrobial Soothing Skin repair Skin brightening

Science

Mechanism of Action

This ingredient exerts its effects through a complex profile of active compounds, including oxindole alkaloids, polyphenols, glycosides, and tannins. These components provide significant antioxidant activity by scavenging free radicals and anti-inflammatory action by suppressing key mediators like TNF-alpha and NF-kappa-B. It also supports skin immunity by stimulating white blood cells and offers antimicrobial properties, which can help defend against microbial growth contributing to conditions such as acne and eczema.

Research

Clinical Evidence

Medium confidence
Effective range 2–4%
Optimal

2%

Key findings

  1. 01 Recommended application concentration for cosmetic formulations focusing on regenerating skin care and anti-aging concepts, ranging from 2-4%. Its antioxidant properties also support skin protection formulations.
  2. 02 In vitro studies at 40 μg/mL demonstrated significant inhibition of superoxide anion generation by 77.3 ± 0.69% and suppression of nitric oxide production by 47.1 ± 0.37%.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 3.9 – 7.5
0 7 14

Stability

A potential change in color may occur during storage, depending on temperature conditions.

Conflicts

  • Formulations should carefully consider high levels of tetracyclic oxindole alkaloids; the European Medicines Agency notes that mixtures with over 0.02% are unsuitable for therapeutic use, indicating a need for precise compositional control.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Uncaria Tomentosa Bark Powder is generally considered safe for short periods of topical use. However, it has not been reviewed by the Cosmetic Ingredient Review (CIR). Oral consumption may rarely lead to mild side effects such as dizziness or headache. The European Medicines Agency (EMA) advises that for therapeutic applications, the concentration of tetracyclic oxindole alkaloids should be below 0.02%.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Uncaria Tomentosa Bark Powder is a valuable botanical active, offering robust antioxidant, anti-inflammatory, and protective benefits suitable for diverse skin types and concerns within precision skincare.

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