Science
Mechanism of Action
This extract deeply hydrates the skin through its rich polysaccharide content (primarily rhamnose, galactose, and glucose), acting as a humectant to draw and bind water, thereby boosting moisture levels. Its antioxidant profile, including bakuchiol and catechin, provides robust protection against free radicals and environmental stressors, which helps diminish the appearance of fine lines and wrinkles. Furthermore, it exerts significant anti-inflammatory effects by inhibiting the release of pro-inflammatory mediators such as nitric oxide, prostaglandin E2 (PGE2), interleukin-6 (IL-6), and interleukin-8 (IL-8), effectively reducing redness, itching, and discomfort. It also offers photoprotective benefits, aiding in the recovery of human fibroblasts exposed to UVA irradiation and preventing collagen degradation by inhibiting MMP-1 activity, while its glycoproteins enhance skin elasticity and moisture retention.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Demonstrated potent anti-inflammatory activity in normal human fibroblast cell lines, achieving complete inhibition of IL-8 release at concentrations above 0.0025%. At 0.1%, it inhibited PGE2 release by up to 85.9% and IL-6 release by 45.6% to 64.5%.
- 02 Enhanced the recovery of human fibroblasts by up to 60.2% after UVA irradiation (3 J/cm2), exhibiting twice the recovery rate compared to UVA-damaged cells without the extract.
- 03 In a contact dermatitis mouse model, it successfully prevented skin lesions caused by consistent DNFB application, suppressed spongiosis, and reduced total serum immunoglobulin and IgG2a levels, indicating significant anti-inflammatory and immunomodulatory effects in vivo.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While pH can influence the solubility and stability of bioactive compounds within bark extracts, a specific optimal pH range for Ulmus Davidiana Bark Extract's stability in formulations has not been established.
Safety
Safety Profile
Although not formally reviewed by the Cosmetic Ingredient Review Expert Panel (CIR), this plant extract is generally recognized as safe by regulatory bodies such as the European Cosmetics Regulation. It possesses a good safety profile, with rare instances of allergic reactions or skin irritation reported, making a patch test advisable, particularly for individuals with sensitive skin. EWG Skin Deep rates it low across categories including cancer, allergies & immunotoxicity, developmental and reproductive toxicity, and use restrictions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Ulmus Davidiana Bark Extract is a valuable, multi-faceted ingredient offering significant hydrating, soothing, anti-inflammatory, and protective benefits suitable for all skin types, especially sensitive and compromised skin.
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