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UGNI MOLINAE LEAF EXTRACT.

Insufficient Data / SKIN CONDITIONING

Derived from the Ugni molinae plant, this leaf extract is a potent botanical offering a spectrum of benefits to the skin. Rich in polyphenols and triterpene acids, it functions as a multi-active ingredient with demonstrated antioxidant, anti-inflammatory, and antimicrobial properties, contributing to overall skin health and resilience.

Antioxidant Anti-inflammatory Antimicrobial Skin conditioning Regenerative Anti-aging Decongestant

Science

UGNI MOLINAE LEAF EXTRACT exerts its effects through a complex profile of bioactive compounds. Its significant antioxidant capacity stems from a high concentration of polyphenolic compounds, including phenolic acids, flavonols, and flavonoids, which effectively neutralize free radicals and mitigate oxidative stress. Anti-inflammatory actions are primarily attributed to triterpene acids like corosolic, alphitolic, and asiatic acids. Additionally, the extract exhibits direct antibacterial properties, and in cosmetic applications, is recognized for decongestant, regenerative, and anti-aging attributes.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An ethyl acetate extract at 12 mg/mL demonstrated significant antimicrobial activity, exhibiting a 19.4 mm inhibition zone against *Staphylococcus aureus*.
  2. 02 Triterpene acids isolated from the leaves, including corosolic, alphitolic, and asiatic acids, showed topical anti-inflammatory potency. Corosolic acid's activity was comparable to nimesulide in an arachidonic acid assay, while all three inhibited TPA-induced inflammation similarly to indomethacin.
  3. 03 In a separate study, Ugni molinae leaf powder at concentrations of 500, 1000, and 1500 mg/kg exhibited antioxidant and antimicrobial effects in food, enhancing oxidative stability and reducing microbial growth, suggesting potential preservative applications.

Transparency

Not commonly dusted

Not applicable based on provided data for topical cosmetic formulations.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While specific pH stability for the leaf extract in cosmetic formulations is not extensively documented, the fruit of Ugni molinae typically presents a pH range of 3.5–5.2, which may inform optimal formulation pH. As with many plant extracts, potential color shifts in the final product should be considered. Its inherent antioxidant properties may contribute positively to overall formulation stability.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Safety assessments by major regulatory bodies such as CIR, SCCS, or FDA have not been found. Available data indicates the ingredient is currently unrated due to ongoing research review. General toxicity data (oral, dermal, inhalation) and GHS classifications are reported as 'None found' by reliable sources, suggesting a lack of specific safety evaluations.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

UGNI MOLINAE LEAF EXTRACT presents promising antioxidant, anti-inflammatory, and antimicrobial benefits for skin, but comprehensive cosmetic-specific efficacy and safety data are currently insufficient for a definitive rating.


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