Science
Mechanism of Action
This extract works by significantly calming skin irritation and reducing inflammation through the suppression of iNOS and COX-2 expression, alongside the regulation of NLRP3 inflammasome, Nrf2, and NF-κB pathways. It provides robust antioxidant protection against environmental stressors and contributes to dermal regeneration with its rich content of polysaccharides, vitamin C, and zinc. Furthermore, specific compounds like trans-cinnamic acid offer cellular protection, while its astringent properties visibly tighten and firm the skin.
Research
Clinical Evidence
Medium confidence1.5%
Key findings
- 01 Recommended use levels of a raw material extract (containing 20% active Tussilago Farfara) between 5-10% in final skincare products translates to an active concentration of 1-2% for soothing, anti-irritant, and antioxidant properties.
- 02 The Tussilago Farfara flower extract raw material is commonly recommended at 5-10% for its ability to calm irritation, provide antioxidant benefits, and offer moisturizing effects.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Store light-protected in a cool, dry place to maintain stability.
Safety
Safety Profile
Tussilago Farfara naturally contains pyrrolizidine alkaloids (PAs), which are known to be hepatotoxic. While toxicity concerns can sometimes be linked to botanical misidentification or PAs from other plants, and PA content can be significantly reduced through controlled cultivation, it is prudent to seek certified low-PA or PA-free sources. Due to these potential safety considerations, utilizing the lowest effective concentration is recommended. No specific cosmetic ingredient review status by CIR, SCCS, or FDA was found for this extract.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While offering diverse skin benefits including soothing and antioxidant properties, the inherent presence of potentially hepatotoxic pyrrolizidine alkaloids necessitates rigorous sourcing and precise dosage consideration, making its general use questionable without certified low-PA content.
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