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TRIS(NONYLPHENYL)PHOSPHITE.

Avoid CAS 26523-78-4 / ANTIOXIDANT

TRIS(NONYLPHENYL)PHOSPHITE (TNPP) is a synthetic chemical primarily utilized as a secondary antioxidant and stabilizer within polymer systems. It functions to protect materials from oxidative degradation and discoloration, with its main applications in industrial sectors like plastics and food contact materials.

Summary

Antioxidant Stabilizer

Science

Mechanism of Action

As a secondary antioxidant, TRIS(NONYLPHENYL)PHOSPHITE operates by effectively decomposing hydroperoxides, which are generated during thermo- or photo-oxidative processes in polymers. This action safeguards polymer chains against thermal oxidative damage and prevents degradation or discoloration. While its mechanism is well-defined in material science, specific details regarding its direct mechanism of action on human skin cells or tissues are not available in the provided research.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The provided research does not indicate this ingredient is used as a 'dusting' agent. Its primary applications are as a stabilizer and antioxidant in polymer manufacturing and food contact materials, not as a direct topical cosmetic ingredient.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

TRIS(NONYLPHENYL)PHOSPHITE is generally described as a hydrolytically stable liquid; however, it may hydrolyze upon contact with water, leading to the formation of phosphoric acid, nonylphenol, and phenol. Optimal stability is maintained under recommended storage conditions, specifically in dry environments away from moisture.

Synergies

  • Primary antioxidants (e.g., hindered phenols)

Conflicts

  • Water (potential for hydrolysis)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

TRIS(NONYLPHENYL)PHOSPHITE is classified with a hazard statement H317, indicating it 'May cause an allergic skin reaction', which signals a high risk of skin sensitization upon repeated or prolonged contact. It is also noted to be slightly irritating to the eyes. While sanctioned by the FDA for use in food contact polymers and cleared for similar applications in several countries, TNPP itself is listed as an Endocrine Disruptor due to probable serious environmental effects. Furthermore, its degradation product, p-nonylphenol, has established endocrine-disrupting properties, a concern even at low potential exposure levels.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to its significant risk of allergic skin sensitization, classification as an endocrine disruptor, and a complete absence of direct efficacy data for skin applications, TRIS(NONYLPHENYL)PHOSPHITE is definitively unsuitable for precision skincare formulations.

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