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TRIPEPTIDE-52.

Insufficient Data / SKIN CONDITIONING

TRIPEPTIDE-52 is an INCI-listed skin conditioning agent, a small peptide comprised of three amino acids. While direct research on this specific peptide is limited, its derivatives are recognized for their potential in skin rejuvenation.

Skin Conditioning Anti-aging (via derivative) Collagen Boosting (via derivative) Elasticity Improvement (via derivative) Wrinkle Reduction (via derivative)

Science

As a fundamental peptide structure, TRIPEPTIDE-52 contributes to the skin's natural protein production, notably collagen. When chemically modified, such as into Palmitoyl Tripeptide-52 Amide, this peptide sequence actively stimulates collagen synthesis, enhances skin elasticity, and visibly diminishes the appearance of fine lines and wrinkles. Its modified form also facilitates improved skin penetration and cellular adhesion.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

Specific optimal pH ranges and stability details for TRIPEPTIDE-52 are not well-documented. However, modifications like palmitoylation can significantly enhance solubility in both aqueous and oil phases, improving stability and prolonged efficacy for its derivatives.


Safety

CIR Status
Insufficient data
Sensitization risk Unknown

No dedicated safety assessments by major regulatory bodies like CIR, SCCS, or FDA for TRIPEPTIDE-52 as a standalone ingredient have been identified. Nevertheless, its derivative, Palmitoyl Tripeptide-52 Amide, is generally regarded as safe for cosmetic application within established guidelines. Precedent from other tripeptides and their derivatives suggests safety at low concentrations, typically below 10 ppm.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While its derivative shows promise for anti-aging and collagen stimulation, direct clinical and safety data for TRIPEPTIDE-52 itself are currently insufficient for a conclusive assessment.


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