Science
Mechanism of Action
This tripeptide primarily operates by precisely blocking the melanocortin 5 receptor (MC5R), which plays a crucial role in regulating sebum production. This targeted action helps to reduce oiliness and promote a mattified skin finish. Beyond this specific mechanism, TRIPEPTIDE-45, like other peptides, generally signals the body to activate endogenous repair pathways, thereby supporting skin regeneration, stimulating collagen synthesis, and modulating inflammatory processes.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Specific data regarding the optimal pH range or stability characteristics of TRIPEPTIDE-45 is currently unavailable. As a general principle, peptides are known to be sensitive to extreme pH conditions, which can compromise their structural integrity and efficacy.
Safety
Safety Profile
TRIPEPTIDE-45 has not been subjected to dedicated safety assessments by major regulatory bodies such as the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or the FDA. While other tripeptides have generally shown safety at typical cosmetic concentrations (e.g., below 10 ppm), these findings cannot be directly applied to TRIPEPTIDE-45 without specific evaluation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While TRIPEPTIDE-45 demonstrates promising efficacy in reducing oiliness and refining pores within a product context, a definitive assessment requires precise concentration data for its pure form and comprehensive, ingredient-specific safety reviews.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources