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TRIPEPTIDE-4.

Insufficient Data CAS - / SKIN CONDITIONING

TRIPEPTIDE-4 refers to a peptide composed of three amino acids. While this specific designation is not a recognized INCI name, general tripeptides are valued in skincare for their ability to support skin regeneration and collagen production.

Skin regeneration Collagen synthesis stimulation Anti-aging Wound healing support Antioxidant (indirect via general tripeptide class) Anti-inflammatory (indirect via general tripeptide class)

Science

As a class, tripeptides are instrumental in promoting skin and tissue regeneration by interacting with cellular receptors. This interaction triggers processes like cell migration, proliferation, and differentiation, vital for repair and renewal. They stimulate collagen synthesis, which is crucial for maintaining skin structure and firmness, and can also encourage the formation of new blood vessels. Certain tripeptides are recognized for additional benefits such as anti-inflammatory, antioxidant properties, and the ability to inhibit glycation and oxidative stress.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The optimal pH range for TRIPEPTIDE-4's stability is not specifically documented due to its non-standardized name. However, peptides generally exhibit greater solubility in aqueous solutions within a pH range of 6–8 compared to more acidic conditions (pH 2–6). Peptides can be susceptible to degradation at elevated temperatures; therefore, some formulations containing peptides may benefit from refrigeration to ensure optimal stability and longevity. Certain tripeptides are known to maintain stability across various pH levels, offering versatility in formulation.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

TRIPEPTIDE-4 is not an officially recognized INCI name, thus specific safety assessments by bodies like the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS) are unavailable. The FDA does not pre-approve cosmetic ingredients. For reference, Tripeptide-1 (glycine-histidine-lysine) has been deemed safe by the CIR Expert Panel for cosmetic use at concentrations typically below 10 ppm, suggesting a generally favorable safety profile for similar peptide structures.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

Due to its non-standard INCI designation, specific clinical efficacy and safety data for TRIPEPTIDE-4 are lacking, preventing a definitive assessment, though the broader class of tripeptides shows promising dermatological benefits.


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