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Moumoujus

TRIPEPTIDE-20.

Valuable CAS - / SKIN CONDITIONING

TRIPEPTIDE-20 is a precision collagen tripeptide designed to enhance skin conditioning and structural integrity. It actively supports the production of key dermal components, contributing to improved skin elasticity and hydration.

Summary

Skin conditioning Enhances skin elasticity Reduces appearance of fine lines and wrinkles Boosts collagen production Improves skin hydration Protects against glycation Supports skin barrier function

Science

Mechanism of Action

As a collagen tripeptide, TRIPEPTIDE-20 functions by stimulating the endogenous production of essential dermal components, including collagen, elastin, and hyaluronic acid. It demonstrates a protective effect against advanced glycated end product (AGE) accumulation and reduces the generation of reactive oxygen species in dermal fibroblasts. Furthermore, it modulates matrix metalloproteinase (MMP) activity, decreasing their induction while promoting an increase in collagen 1 levels. This peptide also fortifies the skin barrier by reducing transepidermal water loss (TEWL) and boosting skin hydration, thereby mitigating the appearance of wrinkles and potentially counteracting inflammation-accelerated degradation of skin's structural integrity.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No specific data is available to indicate that TRIPEPTIDE-20 is commonly dusted in cosmetic formulations.

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 7.5
0 7 14

Stability

TRIPEPTIDE-20 is stable within a pH range of 6.0 to 7.5. As a peptide, it is generally susceptible to degradation at elevated temperatures and requires protection from light exposure to maintain efficacy.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

TRIPEPTIDE-20 itself has not been specifically reviewed by the Cosmetic Ingredient Review (CIR) panel. However, structurally similar tripeptides, such as Tripeptide-1, are considered safe for cosmetic use at concentrations typically below 10 ppm, with a usage range extending to 30 ppm. Both oral and topical clinical studies involving collagen tripeptides, including Tripep20, have reported excellent safety profiles with no observed abnormal symptoms or adverse events. INCI Beauty further indicates a 'No penalty' rating for TRIPEPTIDE-20 across all categories.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

TRIPEPTIDE-20 is a valuable ingredient for enhancing skin's youthful appearance and health, demonstrating efficacy in boosting collagen, improving elasticity, and reducing wrinkles with a favorable safety profile.

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