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TRIPEPTIDE-18.

Insufficient Data CAS - / SKIN CONDITIONING

Tripeptide-18 is a synthetic peptide, consisting of glycine, histidine, and proline, formulated as a skin conditioning agent. It aims to fortify skin structure, reduce visible signs of aging like fine lines, and enhance the skin's overall resilience.

skin conditioning anti-aging

Science

This tripeptide operates by prompting the skin to engage its inherent repair processes, specifically stimulating collagen synthesis. This elevation in collagen fortifies the skin's structural integrity, leading to a diminished appearance of wrinkles and a more even, toned complexion. It also supports the skin's barrier function, helping to prevent dehydration and improving its adaptability to external environmental stressors.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Specific optimal pH and stability data for Tripeptide-18 are not available. However, other tripeptides are often encapsulated in liposomes or nanoparticles to enhance their stability, improve skin penetration, and ensure a controlled release.


Safety

CIR Status
Not reviewed
Sensitization risk Low

No specific safety assessments from CIR, SCCS, or FDA for Tripeptide-18 were identified. However, peptides in general, such as Tripeptide-1 (GHK peptide), have demonstrated a favorable safety profile at low concentrations (e.g., up to 0.002%), with studies indicating negative results for repeated dosage toxicity, skin irritation, sensitization, and genotoxicity.


Your Skin

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While Tripeptide-18 presents a promising mechanism for skin conditioning and anti-aging benefits, direct clinical efficacy and specific safety data for this particular peptide are currently insufficient for a definitive rating.


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