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Moumoujus

TRIPEPTIDE-17.

Valuable CAS - / SKIN CONDITIONING

TRIPEPTIDE-17, also recognized as Myristoyl Pentapeptide-17, is a biomimetic peptide specifically designed to enhance hair growth and density. It operates by stimulating key genetic pathways involved in keratin production, leading to visibly thicker and more robust eyelashes, eyebrows, and hair.

Summary

skin conditioning hair growth

Science

Mechanism of Action

This potent peptide primarily targets hair papilla cells, directly upregulating the expression of keratin genes. This stimulation boosts the synthesis of keratin, the fundamental structural protein of hair, resulting in increased thickness and strength. Furthermore, TRIPEPTIDE-17 contributes to prolonging the active growth phase of hair follicles and can enhance the delivery of other beneficial ingredients within a formulation.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

10%

Key findings

  1. 01 In a care solution containing 10% TRIPEPTIDE-17, participants experienced a 23% increase in eyelash length and density after two weeks, escalating to a significant 71% improvement after six weeks of continuous use.
  2. 02 A polygrowth factor serum incorporating TRIPEPTIDE-17 demonstrated comprehensive improvements in eyelashes over 90 days, including a 10.52% increase in length, 9.3% boost in volume, 11.43% enhancement in luster, 35% greater thickness, and a remarkable 50.83% improvement in curl, with initial results observed as early as 30 days.
  3. 03 In in-vivo studies, formulations with TRIPEPTIDE-17 (at 1000 ppm in base, up to 10% max use) led to an increase in the appearance of fullness and thickness of up to 25% within two weeks and 66% within 28 days of use.

Transparency

Dusting Analysis

Not commonly dusted

No data available to indicate common dusting or specific thresholds for this ingredient.

The Formula

Formulation

Solubility
Water
Optimal pH 3.5 – 4.5
0 7 14

Stability

For optimal stability, TRIPEPTIDE-17 should be incorporated into formulations during the low-temperature water phase. It maintains stability for 18 months when stored refrigerated in a sealed container.

Synergies

  • growth factors
  • lysophosphatidic acid

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While the Cosmetic Ingredient Review (CIR) has not specifically assessed TRIPEPTIDE-17 (Myristoyl Pentapeptide-17), it is generally considered to have a high safety profile, producing no significant side effects. It is deemed suitable for use in delicate areas like the eyelids.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

TRIPEPTIDE-17 is a valuable peptide precisely formulated to significantly enhance the length, density, and overall health of eyelashes and eyebrows by stimulating keratin gene expression.

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