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TRIMETHYL-7-OXABICYCLOHEPTYL)-3-BUTEN-2-ONE.

Optional CAS 23267-57-4 / PERFUMING

TRIMETHYL-7-OXABICYCLOHEPTYL)-3-BUTEN-2-ONE, also known as 5,6-Epoxy-beta-ionone or beta-Ionone epoxide, is primarily employed in cosmetic formulations as a fragrance ingredient. This compound is recognized for its low hazard profile, indicating suitability for its intended use within specified concentrations.

Fragrance

Science

This compound primarily functions by imparting a scent to cosmetic products. While its precursor, beta-ionone, has demonstrated various biological activities, including anti-inflammatory effects, potential for cancer prevention, antimicrobial properties, and stimulation of collagen and hyaluronic acid synthesis in human dermal fibroblasts via glucocorticoid receptor signaling inhibition, these specific mechanisms are not documented for the 5,6-Epoxy-beta-ionone derivative in the available research.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Exhibits good to moderate stability in diverse applications such as fine fragrances, antiperspirants/deodorants, soaps, and shampoos. For optimal preservation, it should be stored in cool, dry conditions within tightly sealed containers, shielded from both heat and light. Proper storage can extend its shelf life to 18 months or longer.


Safety

CIR Status
Not reviewed
Max tested
2%
Sensitization risk Low

The ingredient, specifically 'beta-Ionone epoxide,' consistently does not meet GHS hazard criteria across 115 reports, affirming a low hazard profile. It holds GRAS (Generally Recognized As Safe) status by the FDA as a flavoring agent or adjuvant (FEMA Number 4144, GRAS Number 22). A broader RIFM safety assessment for 'ionone (mixed isomers)' reported no genotoxicity and no skin sensitization concerns at current usage levels. It is not expected to be photoirritating, though its photoallergenic potential was not fully evaluated.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

This ingredient serves as an optional fragrance component, offering a low hazard profile, though direct skincare benefits for this specific derivative are not substantiated by available clinical data.


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