Science
Mechanism of Action
Its isoflavones act as phytoestrogens, improving skin elasticity, stimulating hyaluronic acid, and providing antioxidant protection. It also inhibits collagenase and 5-alpha-reductase, supporting firm skin and reducing sebum production.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 50% effective concentration (EC50) in AP estrogenicity assay for a preformulated red clover extract (35.54% isoflavones).
- 02 50% inhibitory concentrations (IC50s) in estrogen receptor binding assays for a preformulated red clover extract (35.54% isoflavones).
- 03 Treatment with isoflavones from red clover extract in ovariectomized rats increased collagen content, skin thickness, and improved skin moisture over 14 weeks.
Transparency
Dusting Analysis
No data available on common dusting practices for this ingredient.
The Formula
Formulation
Stability
Add during the cool-down phase (below 40°C) to preserve its beneficial compounds, as no specific optimal pH range for stability is identified.
Safety
Safety Profile
Approved by EU Cosmetic Regulation and FDA GRAS for food flavoring. Generally safe, but a patch test is advised, especially for damaged skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Trifolium Pratense Seed Extract is a valuable multi-functional ingredient, offering significant antioxidant, anti-aging, and soothing benefits, suitable for various skin types.
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References
Sources