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TRIETHYLHEXANOIN.

Valuable CAS 7360-38-5 / FRAGRANCE, HAIR CONDITIONING, PERFUMING, SKIN CONDITIONING

Triethylhexanoin is a highly stable, synthetic ester functioning as an emollient, solvent, and skin-conditioning agent. It imparts a desirable light, non-oily texture to formulations while enhancing skin hydration and barrier function.

Emollient Solvent Skin-Conditioning Agent Occlusive Agent

Science

Acting primarily as an occlusive agent, Triethylhexanoin establishes a protective layer on the skin, significantly reducing transepidermal water loss and promoting sustained moisture retention, resulting in plump and smooth skin. Additionally, its solvent capabilities facilitate the dispersion of oil-soluble active ingredients and pigments, improving product spreadability and minimizing stickiness or glossiness.


Research

High confidence
Effective range 3–5%
Optimal

3%

Key findings

  1. 01 Commonly employed at concentrations of 3-5% in leave-on skincare products, according to industry sources like Paula's Choice.
  2. 02 The Cosmetic Ingredient Review (CIR) Safety Assessment reported maximum safe use concentrations up to 100% for face and neck formulations, and 63% for lipstick products.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Triethylhexanoin demonstrates exceptional chemical stability, resisting both oxidation and hydrolysis, and remains robust across extreme pH conditions. It exhibits broad compatibility with a wide range of oils and silicones, making it a versatile formulant.

Synergies

  • Oils
  • Silicones

Safety

CIR Status
Safe as used
Max tested
100%
Sensitization risk Low

The CIR Expert Panel has affirmed Triethylhexanoin's safety for cosmetic applications, noting its metabolic similarity to dietary fats, which minimizes systemic concerns from oral exposure. Dermal application is associated with negligible irritation, and ocular exposure results in, at most, mild irritation. Critically, no evidence of sensitization, photosensitization, or genotoxicity has been observed. Its safety profile is further validated by FDA approval for direct/indirect food additive uses and its inclusion in the EU COSMETICS inventory.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Triethylhexanoin is a valuable, highly stable emollient and solvent, well-tolerated by all skin types, that significantly enhances product texture and supports the skin's barrier function for improved hydration.


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