Science
Mechanism of Action
This extract employs a multi-faceted approach to skin improvement, utilizing powerful antioxidant and anti-inflammatory properties to protect and calm the skin. It actively stimulates skin regeneration by enhancing keratinocyte proliferation, a process facilitated by the activation of ERK1/2 and an increase in mRNA expression of c-fos, c-jun, CTGF, and VEGF, all of which are crucial for effective wound healing and tissue repair. Additionally, it helps to maintain skin hydration, softness, and strengthens the skin's natural barrier.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While plant growth studies suggest a suitable pH range of 4.0–9.0, this observation does not directly correlate with the extract's stability within cosmetic formulations. The extract is noted for its compatibility and ability to integrate well with other natural ingredients.
Synergies
- Harmonizes well with other natural ingredients
Safety
Safety Profile
No specific safety assessments from key regulatory bodies such as CIR, SCCS, or FDA regarding its use in cosmetics were found within the provided research.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Trichosanthes Kirilowii Root Extract is a valuable ingredient for promoting skin regeneration and soothing irritation, supported by promising in vitro data and broad skin compatibility, though further human clinical studies would enhance its profile.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources