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Moumoujus

TRANS-3-HEXENAL.

Questionable CAS 69112-21-6 / PERFUMING

Trans-3-Hexenal is an organic aldehyde primarily recognized for its role as a fragrance and flavoring agent, imparting a fresh, green scent. While commonly incorporated into personal care formulations for its aromatic properties, its direct efficacy or benefits for skin health are not extensively documented.

Summary

Fragrance ingredient

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

As an aldehyde, Trans-3-Hexenal (E)-Hex-3-enal is prone to degradation when exposed to oxidizing agents and should be stored accordingly. It exhibits slight solubility in water (approximately 0.5% at 25°C) and is readily soluble in fat/oil and ethanol.

Conflicts

  • Oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.5%
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) has not formally assessed Trans-3-Hexenal for safety in cosmetic applications. While data indicates its use in fragrance concentrates up to 0.5%, a related isomer, cis-3-hexenal, is classified as an irritant, capable of causing serious eye irritation (Category 2A) and potentially harmful if swallowed, suggesting a need for careful consideration in topical applications.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Primarily a fragrance component with no established skin benefits, Trans-3-Hexenal carries a moderate irritancy risk and its safety in skincare remains unreviewed by the CIR.

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