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TRANS-2-UNDECENAL.

Avoid CAS 53448-07-0 / PERFUMING

Trans-2-undecenal is an aliphatic aldehyde primarily valued for its distinct perfuming characteristics and noted for its potential antimicrobial properties. Its application in precision skincare necessitates careful evaluation due to significant documented risks of skin irritation and sensitization.

perfuming antimicrobial

Science

This compound exhibits antimicrobial characteristics, indicating a potential role as a natural preservative in cosmetic formulations. Current research is also exploring its broader applications in drug development, though its direct mechanism for skin benefit is not clinically established.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

For optimal stability, Trans-2-undecenal should be stored in sealed containers, ideally refrigerated between 0–8 °C, and protected from both light and heat.


Safety

CIR Status
Not reviewed
Sensitization risk High

While Trans-2-undecenal holds approval for flavor use under FEMA and JECFA standards, with JECFA concluding no safety concern at current intake levels in food, its safety profile for topical skin application is concerning. Data indicates it causes skin irritation (H315, 97.8% of reports), may induce an allergic skin reaction (H317, 88.1% of reports), and causes serious eye irritation (H319, 88.1% of reports). The Research Institute for Fragrance Materials (RIFM) has identified its potential to induce skin sensitization in a subset of individuals. Although the International Fragrance Association (IFRA) considers it 'unrestricted' for use in fragrance concentrates, recommending usage levels up to 0.5000% to 1.0000%, protective measures are strongly advised during handling to prevent inhalation and direct skin/eye exposure.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Despite its perfuming qualities and potential antimicrobial benefits, the high risk of skin irritation and sensitization renders Trans-2-undecenal unsuitable for precision skincare formulations.


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