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Ingredient directory

Trametes Hirsuta Extract

Trametes Hirsuta Extract, derived from the Turkey Tail mushroom, is a potent botanical ingredient acclaimed for its dual action as an antioxidant and antimicrobial agent. It actively supports skin health by conditioning and softening, while also offering benefits for hydration and elasticity.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

Antioxidant Antimicrobial Skin Conditioning Emollient Potential Anti-inflammatory Hydrating Elasticity Enhancer Brightening Detoxifying

Science

Mechanism of Action

This extract functions by mitigating oxidative stress through its antioxidant capabilities, neutralizing harmful free radicals that contribute to premature skin aging. It further exhibits antimicrobial activity, aiding in the defense against detrimental microorganisms. Potential anti-inflammatory and immunomodulatory effects may reduce redness and irritation. As a skin conditioner and emollient, it helps maintain epidermal integrity, enhance hydration, and improve skin elasticity. Furthermore, it holds potential for brightening the complexion, reducing hyperpigmentation, and its laccase enzymes may assist in detoxifying environmental xenobiotics.

Research

Clinical Evidence

Medium confidence
Effective range 0.01–3.2%
Optimal

N/A

Key findings

  1. 01 Exhibited significant antioxidant and antimicrobial potential in vitro.
  2. 02 Inhibited the growth of Candida krusei in an in vitro mycelium extract study.
  3. 03 Demonstrated growth inhibition of Candida parapsilosis in an in vitro basidiocarps extract study.
  4. 04 Showed fungicidal effect on Aspergillus glaucus and inhibited other fungal species in vitro (mycelium extract).
  5. 05 Patent claims broadly encompass treatment for various cosmetic conditions, including dry skin, laxity, fine lines, wrinkles, redness, irritation, acne, uneven pigmentation, age spots, rosacea, hyperkeratinization, and eczema.

Transparency

Dusting Analysis

Not commonly dusted

Trametes Hirsuta Extract is a complex botanical extract with multiple reported benefits, not a singular active ingredient prone to 'dusting' at low, ineffective concentrations for marketing purposes.

The Formula

Formulation

Solubility
Water
Optimal pH 3.5 – 8.5
0 7 14

Stability

Laccase enzymes within Trametes hirsuta exhibit optimal activity at pH 3.5 and maintain 100% of their activity across the pH range of 3.5 to 8.5 for six hours. Effective metabolic processes by these enzymes also occur between pH 4 and 6. The beneficial components of the extract are generally water-soluble.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Specific safety assessments from cosmetic regulatory bodies such as CIR, SCCS, or FDA for Trametes Hirsuta Extract are not available in the provided data. Therefore, general EU cosmetics regulations are currently applicable.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Trametes Hirsuta Extract is a valuable ingredient exhibiting significant in-vitro antioxidant, antimicrobial, and fungicidal properties, coupled with promising skin conditioning and hydrating benefits, though further human clinical trials are warranted to fully establish its efficacy and safety profile.

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