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TRACHEA HYDROLYSATE.

Valuable CAS 91080-13-6 / SKIN CONDITIONING

Trachea Hydrolysate is a sophisticated blend of collagen-derived peptides, precisely formulated to enhance skin's fundamental architecture and hydration. It actively promotes de novo collagen synthesis while mitigating enzymatic breakdown, yielding significant improvements in elasticity, moisture retention, and overall textural refinement.

Summary

Emollient Skin-conditioning Antioxidant Moisturizing Anti-aging

Science

Mechanism of Action

This ingredient functions by stimulating fibroblast proliferation and boosting the endogenous production of Type I collagen within the dermal layer, leading to demonstrably smoother and softer skin with improved textural properties. It also exhibits the potential to decrease the expression of matrix metalloproteinases (MMPs), which are enzymes largely responsible for collagen degradation. Chicken trachea hydrolysates specifically contribute antioxidant and bioactive properties. Furthermore, specific collagen-derived peptides, such as Gly-Pro-Hyp and particularly Pro-Hyp, are efficiently transported to the skin following absorption, collectively enhancing skin moisture, elasticity, and reducing transepidermal water loss (TEWL).

Research

Clinical Evidence

Medium confidence
Effective range 8–10%
Optimal

N/A

Key findings

  1. 01 Topical application of related collagen peptides, such as 10% fish scales collagen peptides, has been shown to significantly increase facial skin moisture content and elasticity after 30 days.
  2. 02 Studies on collagen hydrolysates indicate that approximately 8.0% of specific molecular weight peptides (5-13 kDa) can effectively penetrate the skin.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While the optimal pH range for the enzymatic hydrolysis process of chicken trachea, leading to high solubility hydrolysates, is between 6 and 10, the precise optimal pH for the stability of Trachea Hydrolysate within a finished cosmetic formulation has not been specifically defined.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has previously evaluated 'Hydrolyzed Collagen' and concluded its safety for cosmetic applications. Although there is no specific CIR or SCCS assessment directly for 'TRACHEA HYDROLYSATE', its classification within the broader 'Hydrolyzed Collagen' category supports its safety profile for topical use. It also has a generally recognized as safe (GRAS) status by the US FDA for 'Saccharide Hydrolysate' in food use, which suggests a high level of safety for related hydrolysates.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Trachea Hydrolysate is a valuable skin-conditioning agent that supports collagen integrity and boosts hydration, making it highly beneficial for overall skin health and efficacious anti-aging formulations.

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