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TOSYLAMIDE/EPOXY RESIN.

Valuable CAS - / FILM FORMING, PLASTICISER

Tosylamide/Epoxy Resin is a synthetic polymer primarily valued for its robust film-forming and plasticizing capabilities. It is engineered to create a continuous, flexible barrier on surfaces, thereby enhancing product durability and delivering a smooth, refined finish.

Summary

film-forming plasticizer

Science

Mechanism of Action

This ingredient functions by depositing a resilient, non-tacky film upon application, effectively forming a protective layer that improves surface integrity and texture. As a plasticizer, it imparts flexibility and smoothness to formulations, preventing brittleness and contributing to a more supple and enduring product feel.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Consumer testing of products containing Tosylamide/Epoxy Resin at concentrations up to 4% over a period of 1 to 4 weeks demonstrated exceptionally low complaint rates, ranging from 0 to 0.15 complaints per million units tested over three years.
  2. 02 In a Local Lymph Node Assay (LLNA), Tosylamide/Epoxy Resin was not classified as a dermal sensitizer at concentrations reaching up to 50%, representing the maximum concentration evaluated in the study.

Transparency

Dusting Analysis

Not commonly dusted

Tosylamide/Epoxy Resin is a polymer utilized for its film-forming properties, rather than as an active ingredient with specific efficacy thresholds that would typically be subject to 'dusting' in formulation discussions.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This polymer is characterized by its insolubility in water. While hydrolysis as a function of pH was not specifically determined, it is not anticipated to occur within the environmental pH range of 4-9 due to its low water solubility. However, general epoxy resins are known to exhibit diminished stability in strongly acidic or alkaline environments.

Conflicts

  • Solvents that are reactive with epoxy groups, such as ethanol and isopropanol, should be avoided as they may eliminate any residual reactive epoxy functionality within the formulation.

Safety

Safety Profile

CIR Status
Under review/Report planned (2024)
Sensitization risk Low

Although skin sensitization studies (LLNA) did not classify Tosylamide/Epoxy Resin as a dermal sensitizer at concentrations up to 50%, the potential for sensitization in certain individuals cannot be entirely excluded. The Cosmetic Ingredient Review (CIR) Expert Panel previously assessed the analogous Tosylamide/Formaldehyde Resin, concluding its safety as a cosmetic ingredient, a finding reaffirmed in 2004. The Australian National Industrial Chemicals Notification and Assessment Scheme (NICNAS) has not classified Tosylamide/Epoxy Resin as a hazardous substance for skin sensitisation, acute oral toxicity, or skin irritation based on available data. The FDA includes the analogous Tosylamide/Formaldehyde Resin on its list of indirect food additives, permitting its use in polymers that contact food.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Tosylamide/Epoxy Resin is a valuable film-forming and plasticizing agent, offering precise formulation benefits for product durability and textural enhancement with a generally favorable safety profile, particularly in applications where surface modification is key.

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