Science
Mechanism of Action
As a surfactant and cleansing agent, TIPA-Lauroyl Sarcosinate functions by lowering the surface tension of liquids. This property facilitates the mixing of immiscible substances like oil and water, enabling the ingredient to attract, surround, and lift away dirt, excess oil, and other debris from the skin's surface or hair. Being an N-acyl derivative of the amino acid sarcosine, it belongs to the class of amino acid-based surfactants.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Clinical safety assessments by the CIR Expert Panel have established TIPA-Lauroyl Sarcosinate as safe for use up to 5% in leave-on products and up to 15% in rinse-off products, representing the maximum concentrations tested in irritation and sensitization studies.
Transparency
Dusting Analysis
TIPA-Lauroyl Sarcosinate is a surfactant and cleansing agent, typically utilized at functional concentrations to achieve its intended effect rather than being 'dusted' at minimal percentages for perceived efficacy.
The Formula
Formulation
Stability
Sarcosinates generally exhibit robust chemical stability. Its carboxylate group becomes negatively charged at pH levels exceeding approximately 5.5, while the nitrogen atom within its amide linkage maintains a neutral charge across all aqueous pH ranges.
Conflicts
- Strong oxidizing agents
- Ingredients known to facilitate the formation of N-nitroso compounds
Safety
Safety Profile
Safety assessments indicate that while generally safe, formulations must be designed to be non-irritating. A critical restriction is to avoid its use in cosmetic products where N-nitroso compounds could form, as its precursor, sarcosine, can react with oxidizing agents to produce N-nitrososarcosine, a known animal liver carcinogen. The SCCS also places restrictions on its use within the EC Cosmetics Regulation (Annex III). Concentrations are restricted to 5% in leave-on products and 15% in rinse-off products.
Your Skin
Skin Compatibility
Our Assessment
Verdict
TIPA-Lauroyl Sarcosinate is a valuable amino acid-based cleansing agent, offering effective and gentle impurity removal across all skin types when meticulously formulated within established safety parameters.
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