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TILLANDSIA USNEOIDES CALLUS EXTRACT.

Insufficient Data / ANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

Tillandsia Usneoides Callus Extract is derived from the undifferentiated plant tissue of Spanish Moss. It is recognized for its broad potential in skincare, encompassing antimicrobial, antioxidant, and anti-inflammatory attributes.

Antioxidant Anti-inflammatory Antimicrobial Skin Protecting Wound Healing Anti-aging

Science

This extract is rich in bioactive phenolic compounds, including unique flavonoids such as 6,3′,5′-trimethoxy-3,5,7-4′-tetrahydroxyflavone. These components are believed to function as potent antioxidants, offering cellular protection, strengthening capillary walls, mitigating inflammation, and inhibiting the breakdown of skin cells, thereby contributing to anti-aging and skin-protective effects. Its antimicrobial action can also support a balanced skin microbiome.


Research

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies using general Tillandsia usneoides extract (not specifically callus) demonstrated cytotoxic activity against 4T1 breast cancer cells (IC50 = 48.95 ± 3.74 µg/mL), B16-F10 melanoma cells (IC50 = 48.35 ± 5.53 µg/mL), and SW480 colon cancer cells (IC50 = 8.6 ± 1.40 µg/mL), suggesting potential cellular regulatory effects.
  2. 02 General Tillandsia usneoides extracts (methanolic and ethanolic) at 500 mg/mL exhibited significant in vitro antimicrobial activity against skin pathogens. This included S. aureus (22mm zone of inhibition), S. epidermidis (up to 20mm), and P. aeruginosa (up to 23mm).
  3. 03 In vivo research on mice revealed that general Tillandsia usneoides extracts facilitated wound healing, reducing healing time to 12 days compared to 15 days in the control group, indicating regenerative potential.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated Tillandsia Usneoides Callus Extract. While the general Tillandsia Usneoides Extract is noted by EWG as having low concerns, data for the callus-specific extract is insufficient. Paula's Choice suggests a potential for irritation, which may heighten when combined with other ingredients, though this specific ingredient remains unrated.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While general Tillandsia Usneoides extracts show promising biological activities in preliminary studies, specific clinical efficacy and comprehensive safety data for Tillandsia Usneoides Callus Extract are currently insufficient for a definitive assessment.


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