Science
Mechanism of Action
Tiliroside functions through a multifaceted approach: it significantly reduces reactive oxygen species (ROS) and inhibits lipid peroxidation, safeguarding against UV-induced damage and premature aging. Its anti-inflammatory properties involve downregulating pro-inflammatory cytokines and enzymes like COX-2, suppressing NF-κB signaling pathways, and inhibiting MAPK/JNK and MAPK/p38 phosphorylation. Additionally, it offers photoprotection, supports skin barrier function, improves skin resilience, and in vitro/ex vivo studies indicate it induces hyaluronic acid synthesis in keratinocytes and collagen in the dermis.
Research
Clinical Evidence
Medium confidence0.1%
Transparency
Dusting Analysis
The Formula
Formulation
Stability
No specific optimal pH range for tiliroside's stability in cosmetic formulations has been identified. It is soluble in organic solvents (e.g., DMSO, DMF) and oils (e.g., corn oil). For aqueous systems, co-solvents or dispersants such as PEG300, Tween 80, or SBE-β-CD may be required. Tiliroside has a weakly pronounced inherent color.
Safety
Safety Profile
No specific safety assessments from CIR, SCCS, or FDA for cosmetic use were found in the search results, leading to an unknown sensitization risk.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Tiliroside is a valuable multi-functional ingredient, leveraging its potent antioxidant, anti-inflammatory, and hydrating properties to protect skin from environmental damage and reduce the appearance of aging, supported by initial clinical evidence.
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References
Sources