Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

THYMUS ZYGIS OIL.

Valuable CAS 85085-75-2 / SKIN CONDITIONING

Thymus Zygis Oil, derived from the Spanish white thyme plant, is a potent botanical extract recognized for its broad-spectrum antimicrobial properties, including antibacterial and antifungal effects. It also offers antioxidant benefits and contributes to anti-inflammatory and antibiofilm actions, making it particularly suited for formulas targeting oily and congested skin types.

Summary

Antimicrobial Antibacterial Antifungal Antioxidant Anti-inflammatory Antibiofilm Perfuming Skin Conditioning

Science

Mechanism of Action

Acting primarily through its major constituents, thymol and carvacrol, Thymus Zygis Oil disrupts microbial cell membranes, leading to structural damage and disintegration of various bacteria and fungi. Its antioxidant action involves inhibiting lipid peroxidation and neutralizing free radicals. Furthermore, it demonstrates anti-inflammatory effects and inhibits biofilm formation, contributing to comprehensive skin defense.

Research

Clinical Evidence

High confidence
Effective range 0.006–2%
Optimal

N/A

Key findings

  1. 01 Demonstrated non-cytotoxicity to normal human dermal fibroblasts (NHDF) at concentrations between 0.0030% and 0.0125%, maintaining cell viability above 70% for 24 hours.
  2. 02 Exhibited significant antibacterial activity against Staphylococcus aureus strains (e.g., ATCC 25923) with a Minimum Inhibitory Concentration (MIC) of 0.05%.
  3. 03 Potently inhibited biofilm formation of Candida albicans by 58.9% and Candida glabrata by 66.7%, with a minimum inhibitory concentration (MIC) as low as ≤0.006% (≤0.06 µL/mL).
  4. 04 Showcased strong antifungal properties against various strains at concentrations ranging from 0.5 to 10 mg/mL.
  5. 05 Provided antioxidant activity based on the DPPH method, with an IC50 of 2.00 ± 0.15%.
  6. 06 Displayed potent antimicrobial activity, particularly against Gram-negative Enterobacter aerogenes, with MIC50 at 0.147 ± 0.006 mg/mL.

Transparency

Dusting Analysis

Not commonly dusted

As an essential oil, Thymus Zygis Oil is not typically associated with dusting concerns relevant to powdered ingredients.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The stability of key active components, such as thymol, can decrease over time. Optimal preservation of thymol, γ-terpinene, and carvacrol is achieved by freezing and storage at -20 °C.

Conflicts

  • High, undiluted concentrations can cause skin irritation.
  • It is not water-soluble; direct contact of undiluted oil with water may cause skin irritation.
  • Contraindicated for individuals with allergies to thyme or other plants from the Lamiaceae family due to potential cross-reactivity.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
10%
Pregnancy
Caution
Sensitization risk Moderate

Thyme Oil (Thymus zygis) is Generally Recognized As Safe (GRAS) by the FDA (21CFR182.20) for use as a flavoring agent. It is considered suitable for cosmetic application under EU Regulation (EC) No 1223/2009, with natural Methyl Eugenol content limited to 0.03%. Hypersensitivity reactions have been reported. Due to its potent nature, topical application requires dilution, typically up to a maximum of 10% in cream or 20% in vegetable oil. It is not recommended during pregnancy, breastfeeding, or for children under 6 years of age.

Your Skin

Skin Compatibility

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Thymus Zygis Oil is a valuable ingredient for precision skincare, offering potent antimicrobial, antioxidant, and anti-inflammatory benefits, especially for oily and blemish-prone skin, provided it is properly diluted to mitigate its moderate irritancy potential.

Related

Similar Ingredients

Finding similar ingredients…