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Moumoujus

THYMUS VULGARIS EXTRACT.

Valuable CAS 84929-51-1 / PERFUMING, SKIN CONDITIONING

Thymus Vulgaris Extract is a multifaceted botanical ingredient, celebrated for its potent anti-inflammatory, antioxidant, and antimicrobial properties. It actively works to calm skin, protect against environmental damage, and address concerns like acne and excess oil.

Summary

Antioxidant Anti-inflammatory Antimicrobial Astringent Skin conditioning Masking Tonic

Science

Mechanism of Action

This extract functions as a robust antioxidant, effectively neutralizing free radicals to shield skin from environmental stressors and oxidative damage. Its antimicrobial capabilities inhibit bacterial growth, making it beneficial for acne prevention and treatment. The anti-inflammatory action is achieved by soothing irritation, reducing redness, inhibiting enzymes like 5-lipoxygenase (5-LOX), and modulating pro-inflammatory mediators. Furthermore, it acts as a natural astringent, purifying the skin and minimizing the appearance of pores, while also helping to regulate sebum production. It can also condition, moisturize, and form a protective film, contributing to a smoother and softer complexion.

Research

Clinical Evidence

Medium confidence
Effective range 15 µg/mL–51.131 µg/mL%
Optimal

N/A

Key findings

  1. 01 An ethanol extract exhibited significant anti-inflammatory activity by inhibiting 5-lipoxygenase (5-LOX) activity, with an IC50 of 51.131 µg/mL.
  2. 02 Extracts notably reduced IL-6 secretion in activated cells, with concentrations of 15 µg/mL showing significant reduction and 25 µg/mL restoring IL-6 levels to non-activated basal levels.

Transparency

Dusting Analysis

Not commonly dusted

The provided research does not indicate that Thymus Vulgaris Extract is commonly 'dusted' at ineffective concentrations. Clinical efficacy data points to specific effective concentrations in µg/mL.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Specific optimal pH for extract stability is not detailed. However, essential oils derived from Thymus Vulgaris are known for high volatility and low stability, which should be considered in formulation design.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Generally recognized as safe for cosmetic use at appropriate concentrations. Due to its strong aromatic compounds, there is a potential for irritation or allergic reactions in sensitive individuals, manifesting as redness, itching, or dryness, particularly with excessive use. Patch testing is recommended for those with sensitive skin or known thyme allergies. Thyme oils, which share components with the extract, are categorized as Generally Recognized as Safe (GRAS) by the FDA (21 CFR 582.20).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Thymus Vulgaris Extract is a valuable ingredient, offering broad-spectrum benefits from soothing inflammation and combating oxidative stress to managing acne-causing bacteria and refining skin texture.

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